We share our passion for science and the marketplace by helping others succeed as we develop our own technologies in parrallel. Our ramp up process is designed to empower your team and outfit them with the tools they need to succeed. Talk to us today about how we can support your growth, limit your turnover, and put you on a solid track to success and profit.
We are scientists who have worked in small business developing new products for many years. We will listen to you and devise an approach we think will suit your needs. Once approved we will execute and keep you up dated to our progress. Excellent science at a reasonable price.
External resources that provided needed assets to your company are key. Whether you’re seeking a short term project, strategic alliance, guidance with IP protection, help with positioniing your innovative technology for external funding or looking for a special skillset or tool, call us today. Together we’ll create and refine your plan for success.
F. C. Thomas Allnutt, PhD is the President & CSO LLC, a small business focused on new technology development and commercialization. He has experience in industrial research and commercialization of the new technologies either directly or through support of other businesses. Expertise in algal and microbial biotechnology with broad knowledge of related areas. Inventor on >17 patents issued or pending and published >45 peer reviewed papers. His previous positions were as CEO of BrioBiotech LLC, Sr. VP R&D at Phycal Inc., Program Director for the National Science Foundation’s SBIR/STTR Program Biotechnology Group, Research Director at Martek Biosciences, and VP R&D at Advanced BioNutrition.
Broad experience as an industrial scientist. Have expertise in algal biotechnology, algal biofuels & bioproducts, molecular biology in bacteria, yeasts and algae, aquaculture in areas of animal health and nutrition, oral delivery of sensitive bioproducts. Additional experience in grant writing and new product commercialization.
My responsibilities have evolved through small business and government experience - from a bench scientist managing technicians to overall research and development authority for three small businesses (aquaculture health, algal biotechnology and renewable biofuels/bioproducts). Additionally, I managed governmental funding for technology transfer to the marketplace both as a funder of such research (working for the government) and as a grantee (taking innovative technologies to the marketplace). My work style is to focus on the problem and apply available resources to get it done in a rigorous scientific manner in a commercially relevant timeframe. I firmly believe that to build a company on substandard science will doom the company and is not in the interests of any stakeholder. I am direct and to the point yet am able to incorporate the opinions of others in order to focus the team to successfully complete the goal at hand. With my broad experience in biotechnology, I am an asset in both the management of science and operations.
Lane CD, Coury D, Allnutt FCT 2017 Composition and product potential from Auxenochlorella protothecoides, Chlorella sorokiniana and Chlorella vulgaris. Industrial Biotechnology 13(5):270-276
Dhar AK, LaPatra S, Orry A, Allnutt FCT 2017 Chapter 1. Infectious Pancreatic Necrosis. In: Woo PTK and Cipriano RC (eds.) Fish Viruses and Bacteria: Pathobiology and Protection, CABI, pp. 1-12
Dhar AK, Robles-Sikisaka R, Orry A, Allnutt FCT 2016 Chapter 14. Infectious Hematopoietic Necrosis Virus. In: Munir M (ed.) Mononegaviruses of Veterinary Importance Vol. 2 Molecular Epidemiology and Control. CABI, pp. 185-202
Haznedaroglu BZ, Rismani-Yazdi H, Allnutt FCT, Reeves D, Peccia J 2016 Algal biorefinery for high value platform chemicals. In: Brar K, Sarma J, Pakshirajan K (eds.) Platform Chemistry Biorefinery, Future Green Chemistry. Elsevier, New York, pp. 333-360
Kumar A, Perrine Z, Stroff C, Postier BL, Coury DA, Sayre RT, Allnutt FCT 2016 Molecular tools for bioengineering eukaryotic microalgae. Current Biotechnology 5:1-16
Kumar A, Laramore S, Alexander P, Allnutt FCT, Sayre RT 2015 Double stranded RNA simultaneously targeting four white spot syndrome virus (WSSV) genes provides protection against WSSV in Litopenaeus vannamei. Int J Marine Sci Ocean Technol 2(2): 5-10
Bohutskyi P, Liu K, Kessler BA, Kula T, Hong Y, Bouwer EJ, Betenbaugh M, Allnutt FCT 2015 Anaerobic digestion of lipid-extracted Auxenochlorella protothecoides biomass for methane generation and nutrient recovery. Bioresource Technology 183:229-239 doi: http://dx.doi.org/10.1016/j.biortech.2015.02.012
Allnutt FCT, Kessler BA 2015 Chapter 15: Harvesting and Downstream Processing-and Their Economics. In: Biomass and Biofuels from Microalgae. Moheimani NR, McHenry MP, de Boer K, Bahri PA (Eds.) Biofuel and Biorefinery Technologies Vol. 2, pp. 289-310.
Rismani-Yazdi H, Hampel KH, Lane CD, Kessler, BA, White NM, Moats KM, Allnutt FCT 2014 High-productivity lipid production using mixed trophic state cultivation of Auxenochlorella (Chlorella) protothecoides. Bioprocess Biosystems Engineering, p. 1-12 DOI 10.1007/s00449-014-1303-5
Bohutskyi P, Liu K, Kessler BA, Kula T, Hong Y, Bouwer EJ, Betenbaugh M, Allnutt FCT 2014 Mineral and non-carbon nutrient utilization and recover during sequential phototrophic-heterotrophic growth of lipid-rich algae. Appl Microbiol Biotechnol DOI 10.1007/s00253-014-5655-1
Bohutskyi P, Hong Y, Kula T, Kessler BA, Allnutt FCT, Betenbaugh M, Bouwer E 2014 Mixed trophic state production of lipid-rich microalgae feedstock for conversion into biodiesel and biogas. BioEnergy Res, 10.1007/s12155-014-9453-5.
Dhar AK, Manna S, Allnutt FCT 2013 Viral vaccines for farmed finfish. Indian J Virology, doi: 10.1007/s13337-013-0186-4
Dhar AK, Allnutt FCT, LaPatra SE 2013 Chapter 20: Infectious hematopoietic necrosis virus. In: Munir M (ed.) Mononegaviruses of veterinary importance: Pathobiology and Molecular Diagnosis, CABI International, Uppsala, Sweden, pages 308-322
Dhar AK, Allnutt FCT (2011) Challenges and Opportunities in Developing Oral Vaccines against Viral Diseases of Fish. J Marine Sci Res Development S7:001. doi:10.4172/2155-9910.S7-001
Dhar AK, Bowers RM, Rowe CG, Allnutt FCT 2010 Expression of a foreign epitope on infectious pancreatic necrosis virus VP2 capsid protein subviral particle (SVP) and immunogenicity in rainbow trout. Antiviral Research 85:525-531
Dhar AK, Laskhman DK, Amundsen K, Robles-Sikisaka R, Krista KN, Roy S, Hassan KW, Allnutt FCT 2010 Characterization of a Taura syndrome virus isolate originating from the 2004 Texas epizootic in cultured shrimp. Archives Virology 155:315-327
Allnutt FCT, Bowers RM, Rowe CG, Vakharia VN, LaPatra SE, Dhar AK 2007. Antigenicity of infectious pancreatic necrosis virus VP2 subviral particles expressed in yeast. Vaccine 25(26):4880-8
Dhar AK, van Beek NAM, Bullis RA, Allnutt FCT 2008 Transient expression of a heterologous gene driven by promoters isolated from infectious hypodermal and hematopoietic necrosis virus (IHHNV) of shrimp. In: Proceedings of Diseases in Asian Aquaculture, Colombo, Sri Lanka pp 441-449.
Dhar AK, Lakshman DK, Natarajan S, Allnutt FCT and van Beek NAM 2007 Functional characterization of putative promoter elements from infectious hypodermal and hematopoietic necrosis virus (IHHNV) in shrimp and insect and fish cell lines. Virus Research 127(1):1-8
Banks HT, Bokil VA, Hu S, Dhar AK, Bullis RA, Browdy CL, Allnutt FCT 2006 Modeling shrimp biomass and viral infection for production of biological countermeasures. Mathematical Biosciences & Engineering 3(4), 635-660
Dhar, AK, Allnutt FCT 2008 Taura Syndrome Virus. Encyclopedia of Virology, Third Edition 5:1-8. (Eds.) Brian Mahy and Marc van Regenmortel
Dhar AK, Lakshman DK, Natarajan S, Allnutt FCT, van Beek NAM 2007 Functional characterization of putative promoter elements from infectious hypodermal and hematopoietic necrosis virus (IHHNV) in shrimp and in insect and fish cell cultures. Virus Research 127(1), 1-8
Toole CM, Allnutt FCT 2003 Chapter 14. Red, cryptomonad and glaucocystophyte algal phycobiliproteins. In: Larkum AW, Douglas S, Raven JA (eds.) Photosynthesis in Algae, Kluwer Academic Publishers, The Netherlands, pp. 305-334.
Telford WG, Moss MW, Morseman JP, Allnutt FCT 2001 Cyanobacterial stabilized phycobilisomes as fluorochromes for extracellular antigen detection by flow cytometry. J Immunol Meth 254, 13-30
Telford WG, Moss MW, Morseman JP, Allnutt FCT 2001 Cryptomonad algal phycobiliproteins as fluorochromes for extracellular and intracellular antigen detection by flow cytometry. Cytometry 44, 16-23
Lobel LI, Morseman JP, Zeng, X, Lustbader JW, Chen H, Allnutt FCT 2001 Development of a fluorescence based high throughput assay for antagonists of the human chorionic gonadotrophin receptor extracellular domain: Analysis of peptide inhibitors. J Biomolecular Screening 6(3), 151-158
Zoha SJ, Morseman JP, Ramnarain S, Moss MW, Allnutt FCT, Harvey B, Colby S 1999 PBXL dyes provide sensitive and direct fluorescent detection. J Fluorescence 9(3), 197-208
Morseman JP, Moss MW, Zoha SJ, Allnutt FCT 1999 PBXL-1: A new fluorochrome applied to detection of proteins on membranes. BioTechniques26, 559-563
Zoha, SJ, Ramnarain S, Allnutt FCT 1998 High sensitivity fluorescent immunoassay for thyroid stimulating hormone (TSH) using PBXL™ dyes. Luminescence Forum 4, 10-14
Morseman J, Moss M, Zoha S, Allnutt FCT 1998 PBXL™-1: A new fluorochrome for detecting protein on membranes. Dual HelixSummer, 1-4
Zoha SJ, Ramnarain S, Allnutt FCT 1998 Ultrasensitive direct fluorescent immunoassay for thyroid stimulating hormone. Clinical Chemistry 44, 2045-2046
Allnutt FCT 1996 Cyanobacterial (Bluegreen algal) biotechnology: Past, present and future. J Scient Indust Res 55, 693-714
Parker BC, Radmer RJ, Allnutt FCT, Chen H 1994 Microalgal biotechnology and commercial applications: Introduction. J Appl Phycology 6, 91-92
Allnutt FCT, Ewy R, Renganathan M, Pan RS, Dilley RA 1991 Nigericin and amine effects on localized proton gradients in thylakoids. Biochim Biophys Acta 1059, 28-36
Renganathan M, Pan R-S, Ewy RG, Theg SM, Allnutt FCT, Dilley RA 1991 Evidence that localized energy coupling in thylakoids can continue beyond the energetic threshold onset into steady illumination. Biochim Biophys Acta 1059, 16-27
Allnutt FCT, Dilley RA, Kelley TA 1989 Effect of high KCl concentrations on membrane-localized metastable proton buffering domains in thylakoids. Photosyn Res 20, 161-172
Allnutt FCT, Atta-Asafo-Adjei E, Dilley RA 1989 Chloroplast thylakoid proteins associated with sequestered proton buffering domains. Plastocyanin contributes buffering groups to localized proton domains. J Bioenerg Biomembranes 21, 535-551
Allnutt FCT, Bonner WD 1987 Correction of freezing artifacts in the application of electron paramagnetic resonance for quantification of the reduction of ferric-hydroxamate by Chlorella vulgaris. Plant Physiol 83, 739-741
Allnutt FCT, Bonner WD 1987 Characterization of iron uptake from ferrioximine B and ferric-rhodotorulic acid by Chlorella vulgaris. Plant Physiol 85, 746-750
Allnutt FCT, Bonner WD 1987 Evaluation of reductive release as a mechanism for iron uptake from ferric-hydroxamates by Chlorella vulgaris. Plant Physiol 85, 751756
Allnutt FCT, Bonner, WD 1984 Characteristics of iron uptake from hydroxamate siderophores by Chlorella vulgaris and correlation between uptake and reduction. J Plant Nutrition 7, 427-435
Parker BC, Boyer S, Allnutt FCT, Seaburg KG, Wharton RA, Simmons GM 1982 Soils from the Pensacola Mountains, Antarctica. Soil Biol Biochem 14, 265-271
Parker BC, Simmons GM, Seaburg KG, Cathey DD, Allnutt FCT 1982 Comparative ecology of plankton communities in seven Antarctic oasis lakes. J Plankton Res 4, 271-286
Allnutt FCT, Parker BC, Seaburg KG, Simmons GM 1981 In situ nitrogen (C2H2) fixation in lakes of Southern Victoria Land Antarctica. Hydrobiological Bulletin (Amsterdam) 15, 99-109
Simmons GM, Parker BC, Allnutt FCT, Brown DP, Cathey DD, Seaburg KG 1979 Ecosystems comparison of oasis lakes and soils. Antarctic J US 24,181-183
Parker BC, Howard RV, Allnutt FCT 1978 Summary of environmental impact assessment of the Dry Valley Drilling Project. In: BC Parker and MC Holliman (eds), Environmental Impact in Antarctica, VPI Press, Blacksburg, Va. pp. 211-251
Parker BC, Ford AB, Allnutt FCT, Bishop B, Wendt S 1977 Baseline microbiological data for soils of the Dufek Massif. Antarctic J US 12, 24-26
Dhar AK, Allnutt FCT 2013 System for production of vaccines and therapeutics in host and non-host species and compositions thereof. US Provisional Application
ASSIGNED TO PHYCAL INC.
Lane CD, Allnutt FCT, Driza K, Lakshminarayanan K 2012 Lipid recover from water with hydrophobic resin. US Provisional 61/647,247
Abad MS, Postier B, Swanson A, Lauderdale GW, Kessler B, Allnutt FCT, Park JD, Spoo-Chupka M, Slomczynski DJ, Kwiatkowski JR 2012 Methods for improved mixed trophic state algal culture. WO/2012109375
Lane CD, Swanson AK, Brister AB, Allnutt FCT 2009 Biofuel production from algae. PCT Patent Application WO/2010/132414, US20120095245
Allnutt FCT, Postier BL, Sayre RT, Coury DA 2009 Biofuel from recombinant oleaginous algae using sugar carbon sources. WO2011026008; US2012/01566717
Allnutt FCT, Postier BL, Sayre RT, Coury, DA, Kumar A, Swanson A, Abad MS, Perrine ZG 2009 Biosecure genetically modified algae. WO/2012006307
ASSIGNED TO ADVANCED BIONUTRITION:
Dhar AK, Allnutt FCT 2011 Crustacean expression vector. PCT Publication WO 2005/102041. (Filed 4/15/2004; Published 11/3/05); US Patent 7,973,148 (Issued 12 April 2011)
Barratt R, Allnutt FCT, Bullis R, Kyle DJ 2009 Crustaceans as production systems for therapeutic proteins. US Patent 7,550,647 (Issued 23 June 2009)
Barratt R, Allnutt FCT, Bullis R, Kyle DJ 2011 Crustaceans as production systems for therapeutic proteins. US Patent 7,932,056 (Issued 26 April 2011)
Dhar AK, Bowers RM, Allnutt FCT 2012 Antigenicity of infectious pancreatic necrosis virus VP2 sub-viral particles expressed in yeast. US Patent 8,221,767
Dhar A, Allnutt FCT 2004 Protein and peptide expression for passive immunity. PCT Publication WO 2004/025263; US20060120999 (Filed 9/15/2003; Entered National Phase in the European Union, India, Japan, and the U.S.)
Allnutt FCT, Harel M 2003 Incorporation of anaerobic bacteria in feed formulations. PCT Publication WO03/089579 (Filed 4/15/2002; Entered National Phase in the U.S.).
Allnutt FCT, Harel M 2003 Enclosed aquacultural systems for production of purified recombinant proteins. PCT Publication WO30/087812 (Filed 4/9/2002; Entered National Phase in the European Union and the U.S.).
Allnutt FCT, Kyle DJ 2004 Viruses and virus-like particles as multiple antigen and target display. PCT Publication WO 2004/003143; US20060121468 (Filed 6/26/2002; Entered National Phase in the European Union, Canada, and the U.S.).
ASSIGNED TO MARTEK BIOSCIENCES CORP:
Morseman JP, Moss MW, Allnutt FCT 2007 High fluorescent intensity cross-linked allophycocyanin. US Patent 7,256,050
Apt KE, Allnutt FCT, Kyle DJ, Lippmeier, JC 2011 Trophic conversion of obligate phototrophic algae through metabolic engineering. US Patent 7,939,710 (Issued 10 May 2011)
Apt KE, Allnutt FCT, Kyle DJ, Lippmeier JC 2011 JC 2011 Trophic conversion of obligate phototrophic algae through metabolic engineering. US Patent 8,008,061 (Issued 30 August 2011)
Allnutt FCT, Kyle DK, Grossman AR, Apt KE 2000 Methods and tools for transformation of eukaryotic algae. US Patent 6,027,900(Issued 22 Feb. 2000)
Brown JM, Allnutt T, Chen H, Radmer R 1998 Combinatorial libraries of labeled compounds and methods of producing same. US Patent 5,741,713 (Issued 21 April 1998)
Allnutt FCT, Toole CM, Morseman J 2001 Recombinant phycobiliprotein and phycobiliprotein linker fusion proteins and uses therefore. US Patent Application Publication US 2001/0055783 A1 and PCT Patent Application WO0196871
Allnutt FCT, Kyle DK, Grossman AR, Apt KE 1997 Methods and tools for transformation of eukaryotic algae. PCT Patent Application WO9739106
Allnutt FCT, Morseman JP, Chen H filed 2000 Specific binding assay for docosahexaenoic acid. PCT Publication WO00/58734
Brown JM, Allnutt FCT, Chen H, Radmer R 1997 Combinatorial libraries of labeled biochemical compounds and methods for producing same. PCT Patent Application WO9700887
Allnutt FCT Photosynthetic production of stable isotopically labeled recombinant proteins. US Provisional Patent Application and PCT Patent Application WO9718321
Allnutt FCT, Johnson TV, Apt KE, Zoha SJ Modified whole cells as fluorescent labels. US Provisional Patent Application